icon Centaurium cachanlahuen (Mol) B.L.Rob.

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Synonymes Erythraea chilensis Pers.Gentiana cachanlahuen Mol.
Family Gentianaceae
Description

Annul herb 5-40 cm in height, erect, glabrous; Stems quadrangular, sub-alate, dichotomously branching; Leaves opposite, sessile, entire. Inferior leaves oblong-lancoelate or oval, acute, 1-3 cm long by 0.5-2 cm wide; Superior leaves smaller, linear or narrowly lanceolate; Inflorescence drooping panicles or terminal cymes, usually dichotomous; Flowers intense pink, peduncles 1-4 mm length; Tubular calyx 5-10 mm long with 4-5 laciniae longer than the calyx tube, sublinear, acute; Hypocrateriform corolla, tube 8-12 mm long, limb 3-6 mm long, 4-5 lobed, lobes elliptical-oblongate, obstuse. Stamens 4-5, opposite to petals, adnate to the corolla; Filaments simple; Anthers oblong, linear, spiral after flowering; Ovary oblong; Style filiform; Stigma bi-lamellate; Fruit in membranous capsule, veined, linear-oblong up to 1.2 cm long; Seeds numerous, oval, rough, sub-alate, 0.2-0.3 mm long.

Image gallery
Crude drug
Aerial parts of the plant
Common names

Cachanlahuen, Cachanlagua, Cachen cachanlaui, Kachan-l-lawen, German: Tausendgüldenkraut

Parts used

All plant parts have therapeutic properties

Major uses

C. cachanlahuen has been widely used for its therapeutic qualities and is well known as a febrifuge and hypotensor. The leaves are antihelmintic (taken on an empty stomach), anti-rheumatic, blood purifying and useful in skin complaints (Hoffmann, 2001). According to Murillo et al., 1889, it is used in chronic rheumatism, pleurodynia, amenorrhea, and in patients recovering from pneumonia or pleurisy.


Country specific information available for Icontop IconCollapse
Chile

Trade information Icontop IconCollapse
Average price

In the Mapuche pharmacy ‘Makelawen’, an extract of C. cachanlahuen is sold for US$ 3.68. In Peru it is sold as a powdered herb for US$ 20 per 50 g, as a whole dried herb for US$ 5 per 50 g and as capsules for US$ 20 for 100 capsules.

Plant material

Wild

Areas of production

This species is an annual herb. It is endemic to Chile and has a distribution between Atacama and Valdivia, from the Andes Mountains to the coast. It is also present in the Juan Fernández Archipelago.

Plant products

Crude and semi-processed. Powdered, dried and encapsulated homeopathic preparations.

Special regulations

None reported

Trade points
-> Farmacia Mapuche
Contact: Makelawen
Avda. Providencia # 2362, Santiago
Chile
Tel: 3334835
Website: http://www.farmaciamapuche.cl/Farmacia_local/makewelawen/inicio.
-> Asociación de Hierbateros Vega Poniente
Maquinista Escobar Santiago de Chile c/o Bernardo Reyes
Chile
-> Agrocomercial Herbal Chile Ltda.
Chile
Tel: 56 45 286390
Website: www.herbachile.com
-> CAMBIASO HNOS. S.A.
Chile
Tel: 56 32 213674
Website: www.cambiaso.cl/
-> Ximena Polanco (Dresden Street 4640
San Miguel
Chile
Website: www.xpolanco.com

Available sources of technologies Icontop IconCollapse
Cultivation

No data available regarding the cultivation of this species. It is reported to be easily propagated from seed sown directly in seed trays (Hoffmann, 1992).

Harvesting

The material should be kept in storage places, dried and packed.

Phyto-pharmaceuticals

Natusalub Canchanlagua, Medicinal Plants (powdered, dried and encapsulated).

Av. Alfredo Mendiola
Cdra 17 / S.M.P.
Centro Comercial FIORI
227 - A 2do Piso
E-mail: ventas@natusalub.com

Herbal drugs

In the Mapuche pharmacy ‘Makelawen’, a homeopathic preparation of C. cachanlahuen is made.


Scientific Information Icontop IconCollapse
Ethno-botanical info

This species has been well known for its medicinal properties for centuries. The name cachanlahuen is mapudungun- the language of the Mapuche. It is a compound word which comes from the word “kacán”, which means “side ache” and “lawen” which means remedy; and literally translated means “side ache remedy” (Gungkel, 1960). This ancestral knowledge has translated into the modern use of this herb against Pleurodynia. A study realized in the Mapuche community of Currihuinca, (near San Martín de los Andes, Argentina) regarding medicinal plant knowledge showed that C. cachanlahuen was a species of great value to the community, with 27% of the people interviewed using the plant. Additionally C. cachanlahuen is used with a high degree of consistency (69%) as an anti-inflammatory-analgesic, and as the third in importance (Estorba et al., 2004).

Pharmacological studies

The Gentianaceae family contains many species with interesting phytochemical properties. They have been widely used in traditional medicine and as constituents in bitters and similar concoctions. For this reason members of this family have been well studied (Jensen and Schripsema, 2002). C. cachanlahuen contains xanthones, which are known to have anti-inflammatory, antifungal and antibacterial properties (Muñoz et al., 1999).

Insunza et al., 2001 reported that the whole plant extract had nematocide activity on Xiphinema americanum, an economically important vineyard pathogen.

Chemical constituents
Major chemical constituents

Chemical studies of C. cachanlahuen have led to the isolation of swertiaperenine, swerchirine, decusatine, 1,8-dihidroxy-2,3,4,6-tetrametoxy-9H-xanthone. It was also found to contain oleanolic acid and bitter substances such as iridoids, particularly sweroside (Versluys et al., 1982).

Quality control
Anatomical description Source: Montenegro et al 2004
Safety data

According to regulations imposed by MERCOSUR, C. cachanlahuen is registered as a condiment of botanical origin. It is used as a fruit or for its properties as an aromatizer or flavouring and consequently there are no restrictions regarding those plant parts which are used in normal consumption.

Contraindications

None known

Drug interactions

None known

Dosage

An infusion can be prepared using a pinch of the herb in one cup of boiling water. Drink two cups a day as a stimulant, emmenagogue, hipotensor and diaphoretic. Alternatively soak one teaspoon of the dried herb in a cup of cold water overnight. Drink on an empty stomach as a depurative, tonic, to alleviate intercostal neuritis and in convalescence.

Monographs
  • Montes, M. and Wilkomirsky, T., 1985, Medicina Tradicional Chilena. Editorial Universidad de Concepción. pp 201
  • Muñoz, O., 1992, Química de la Flora de Chile. Departamento Técnico de Investigación. Universidad de Chile. pp 251

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References Icontop IconCollapse
  • Colección textos Universitarios, Vicerrectoría de Asuntos Académicos. Universidad de Chile. pp 330
  • Estomba, D., Ladio, A. and Lozada, M., 2004, Medicinal wild plant knowledge and gathering patterns in a Mapuche community from North-western Patagonia. Journal Ethno-pharmacology. Available at: http://www.sciencedirect.com/science?_ob=ArticleListURL&_method=list&_ArticleListID=532724460&_ sort=d&view=c&_acct=C000023959&_version=1&_urlVersion=0&_userid=496749&md5=7af4c7 bdf1641b58af593952b4c18b53
  • Hoffmann, A., 1978, Flora Silvestre de Chile, Zona Central. Ed. Fundación Claudio Gay.
  • Insunza, V., Aballay, E. and Macaya, J., 2001, In vitro nematicidal activity of aqueous plant extracts on Chilean Populations of Xiphinema americanum sensu lato. Nematropica, 91: 47–54
  • Jensen, S. R. and Schripsema, J., 2002, Chemotaxonomy and pharmacology of Gentianaceae. Gentiaceae-Systematics and Natural History. Cambridge University Press. Available at: http://organisk.kemi.dtu.dk/SRJ/Gentianaceae_Chemotaxonomy.pdf
  • López, R. et al., 2004, Estudio químico y de bioactividad de Solanum ligustrinum y Centaurium cachanlahuen. Available at: http://www.upa.cl/direcciongeneraldeinvestigacion/P2004.pdf (19 May 2005)
  • Montes, M. and Wilkomirsky, T., 1985, Medicina Tradicional Chilena. Editorial Universidad de Concepción. pp 201
  • Muñoz, O., 1992, Química de la Flora de Chile. Departamento Técnico de Investigación. Universidad de Chile. pp 251
  • Muñoz, O., Montes, M. and Wilkomirsky, T., 2004, Plantas Medicinales de Uso en Chile. Química y Farmacología.
  • REGLAMENTO TÉCNICO MERCOSUR SOBRE ADITIVOS AROMATIZANTES/SABORIZANTES (DEROGACIÓN DE LA RES. GMC N° 46/93). Available at: http://www.puntofocal.gov.ar/doc/0405.pdf
  • Versluys, C., Cortés, M., López, J. T., Sierra, J. R. and Razmili, I., 1982, A novel xanthone as secondary metabolite from Centaurium cachanlahuen, Cellular and Molecular Life Sciences, 38(7)
  • Wilhelm, E., 1992, Botánica Indígena de Chile. Ed. Andrés Bello.